7th NovAliX Conference

Biophysics in Drug Discovery 2019 | Asian Edition

Developing the Synergy between Biophysics and Medicinal Chemistry to Deliver Better Drugs

 Kyoto, Japan    November 13-15, 2019

Programme


13:00

Registration

13:45

Welcome Address

Session 1: Recent Advances in FBDD

Session Chair

Dr Michael HANN
GSK MEDICINES RESEARCH CENTRE, Stevenage, United Kingdom

14:00

PhABits – Shining New Light on Fragments Approaches for Assessing Targets Tractability (IL01)

Dr Michael HANN
GSK MEDICINES RESEARCH CENTRE, Stevenage, United Kingdom

14:30

Ligand-Based Fluorine NMR Screening in Drug Discovery (IL02)

Dr Anna VULPETTI
NOVARTIS, Basel, Switzerland

15:00

Enabling Drug Discovery with Crude Reaction Mixture Screening (IL03)

Dr Ben DAVIS
VERNALIS RESEARCH, Cambridge, United Kingdom

15:30

Coffee Break

16:00

Oral Communication 01

Mr Andreas LANGER
NANOTEMPER TECHNOLOGIES GMBH, Munich, Germany

16:15

Oral Communication 02

Mr Md Habibur RAHAMAN
UNIVERSITY OF QUEENSLAND, Brisbane, Australia

16:30

Oral Communication 03

Dr Kenneth CAMERON
CRUK BEATSON INSTITUTE, Glasgow, United Kingdom

Keynote Speaker (Industry)

Session Chair

Dr Michael HANN
GSK MEDICINES RESEARCH CENTRE, Stevenage, United Kingdom

16:45

From Fragments to Pharmaceuticals (KL01)

Dr Harren JHOTI
ASTEX PHARMACEUTICALS, Cambridge, United Kingdom

17:45

Welcome Reception

19:00

End of the Day

09:00

Registration

Session 3: Challenging Targets (GPCRs, Ion Channels...)

Session Chair

Dr Junichi SAITO
KYOWA KIRIN CO., LTD., Shizuoka, Japan

09:30

Advancing Cryo-EM for Determination of G Protein-coupled Receptor Structure (IL04)

Prof. Patrick M. SEXTON
MONASH UNIVERSITY, Parkville, Australia

10:00

Structural Biology of Seven-Transmembrane Receptors Toward Drug Discovery (IL05)

Prof. Shigeyuki YOKOYAMA
RIKEN, Yokohama City, Japan

10:30

Coffee Break

11:00

Oral Communication 04

Dr Morishita ELLA
VERITAS IN SILICO, Tokyo, Japan

11:15

Oral Communication 05

Mr Masahiro HIRAIZUMI
MITSUBISHI TANABE PHARMA CORPORATION, Yokohama, Japan

11:30

Poster Session

12:30

Lunch & Networking

Session 4: Cryo-EM in Drug Discovery

Session Chair

Dr Midori KAMIMURA
TEIJIN PHARMA LIMITED, Tokyo, Japan

14:00

Advancing Drug Discovery in Pharma Using Cryo-EM (IL06)

Dr Claudio CIFERRI
GENENTECH, South San Francisco, United States

14:30

Oral Communication 06

Dr Simon HOLTON
BAYER , Berlin, Germany

14:45

Oral Communication 07

Dr Wen-ti LIU
NOVALIX, Illkirch, France

15:00

Coffee Break

Session 5: X-ray Crystallography / Cryo-EM Complementarity

Session Chair

Dr Denis ZEYER
NOVALIX, Illkirch, France

15:30

Increased Performance in High-Throughput Compound and Fragment Screening Campaigns by the Use of "Club Class" Data Collection (IL07)

Dr Gerard BRICOGNE
GLOBAL PHASING LTD., Cambridge, United Kingdom

16:00

Applying Hybrid Biophysical and Structural Methods to Study Allosteric Regulation of GTP Cyclohydrolase I - A Target for Treating Inflammatory and Neuropathic Pain (IL08)

Dr Herbert NAR
BOEHRINGER INGELHEIM, Biberach, Germany

16:30

Structural Studies of the Yeast Fatty Acid Synthase. The Discovery of a Novel and Overlooked Subunit (IL09)

Prof. Holger STARK
MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY, Göttingen, Germany

17:00

Posters & Drinks

18:30

End of the Day

19:30

Conference Dinner

08:30

Registration

Keynote Speaker (Academia)

Session Chair

Prof. Daniela RHODES
NANYANG TECHNOLOGICAL UNIVERSITY, Singapore, Singapore

09:00

Structure-biophysics Driven PROTAC Design for Degrading Undruggable Cancer Targets (KL02)

Prof. Alessio CIULLI
UNIVERSITY OF DUNDEE, Dundee, United Kingdom

Session 5: Hot Topics

Session Chair


Prof. Daniela RHODES
NANYANG TECHNOLOGICAL UNIVERSITY, Singapore, Singapore

10:00

The Roles of G-quadruplex DNA in Biology and as Drug-targets (IL10)

Prof. Daniela RHODES
NANYANG TECHNOLOGICAL UNIVERSITY, Singapore, Singapore

10:30

Coffee Break

11:30

Oral Communication 08

Mr Dzung NGUYEN
PHILIPPS-UNIVERSITÄT MARBURG, Marburg, Germany

11:45

Oral Communication 09

Prof. Chunyu WANG
RENSSELAER POLYTECHNIC INSTITUTE, Troy, United States

12:00

Poster Prizes and Closing Remarks

12:30

End of the Conference