Developing the Synergy between Biophysics and Medicinal Chemistry to Deliver Better Drugs
BφDD 2013
Strasbourg, France October 15-18, 2013
Registration
Social Programme
Welcome Address
Chair
KN01 - Biophysical Methods and Fragment Based Drug Discovery: Targeting Protein-Protein Interactions in Cell Regulatory Systems
Welcome Reception
Registration
PL01 - Binding of Drug Substances to Molecular Targets Investigated by Biophysical Methods
PL02 - Enabling GPCR Drug Discovery Through Structural and Biophysical Insights
Coffee Break
OC01 - Biophysical Investigations of the Synergistic Activities of Antimicrobial Peptides: New Strategies to Fight Multiresistance
OC02 - X-Ray Crystallography, Kinetic Target-Guided Synthesis and NMR to Unravel the Mode of Action of Insulin Degrading Enzyme Modulators
Lunch and Networking
PL04 - Protein Methyltransferase Inhibitors as Personalised Cancer Therapeutics: DOT1L and EPZ-5676
PL05 - Investing in Knowledge: Combining Biophysical Data in Fragment-Based Drug Discovery
OC03 - Residence and Recognition Time and their Use for Structure Kinetic Relationships and for Judging Efficacy of Lead Series
OC04 - Pharmacokinetics and the Drug-Target Residence Time Concept
Coffee Break
OC05 - Bringing Light into Antibody Binding Characteristics in Crude Extracts by Means of FCCS
PL06 - Can we Use Kinetics and Thermodynamics to Guide Drug Discovery?
KN02 - Molecular Mechanism of Action (MMOA) in Drug Discovery
Entertainment (optional & subject to prior registration)
PL07 - Label-Free, Immobilisation-Free Interaction Studies Using Microscale Thermophoresis
PL08 - Backscattering Interferometry: An Enabling Drug Development Technology
OC06 - Detection and Analysis of Proteins with an Electro-Switchable DNA Chip
Coffee Break
OC07 - Binding Rate Constants Measured on Microliter Volume Using On-Chip Temperature Modulation and Fluorescence Lock-In Detection
OC08 - CRYO-TEM: The Way to Answer Real Biological Questions through Unraveling the 3D Mechanistics of Protein
PL09 - Towards Personalised Cancer Medicine with New NMR Tools to Probe Small GTPase Proteins
Lunch and Networking
Poster Session
Coffee Break
Round-table discussion on hot topics, emerging trends, and new techniques & approaches; sharing of experience and questions from the audience to a panel of experts
Poster Prizes
KN03 - Combining X-Ray Crystallography and Single-Molecule Methods to Probe Antibiotic Inhibition of Translation
Conference Dinner (optional & subject to prior registration)
Chair
PL10 - Application of SPR Biosensors Throughout the Drug Discovery Process
PL11 - Finding Active Ligands to kRAS Using Solution State NMR
Coffee Break
OC09 - Identification and Validation of Small Molecule Inhibitors of G Protein Beta 1 Gamma 2
OC10 - Fragments at UCB: Implementation of Non-Covalent Mass Spectrometry and 19F NMR as Orthogonal Screening Techniques
PL12 - Biophysics in Pharmaceutical Lead Discovery
Closing Remarks and Departure